LGALS3 knockout
Intervention1 paper1 finding
- Animals1
Outcomes
1Retinal degeneration
downin mice1
1 study
Retinal degeneration
downin mice1
LGALS3 knockout protects against retinal degeneration in mice.
Animalslater-stage degeneration under prolonged lipid burdenretina
Lack of dietary DHA drives harmful lipid remodeling and retinal degeneration in mice · bioRxiv · 28 Sep 2026 · Preprint
Latest
1Lack of dietary DHA drives harmful lipid remodeling and retinal degeneration in mice
Restoring the fatty acid reversed visual decline in mice and cleared toxic oxidized lipids that otherwise trigger chronic microglial activation.