Lentinan

1 paper4 findings

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Labs are independent when their papers share no last author and no institution.

Against: findings that point the other way from most findings on the same outcome.

On aging: the drug’s trials ARN judged to be about aging, of every trial that tests it for any use.

No results posted: trials that ended more than a year ago with no results on ClinicalTrials.gov and no paper in ARN’s record.

Company ties: findings with an author at a company, or from a paper whose competing-interests statement declares ties to one.

1 lab in 1 country

Funder: Natural Science Foundation of Hebei Province

Animals1

Outcomes

Mitochondrial biogenesis (PGC-1α)

upin animals1

1 study

Lentinan activates mitochondrial biogenesis (PGC-1α).
“low and medium doses of LNT significantly increased mitochondrial abundance”
Animalsin differentiated C2C12 and skeletal muscle tissues
Lentinan mitigates age-related sarcopenia through the promotion of mitochondrial biogenesis
Food research international (Ottawa, Ont.)16 Jan 2026

More on Mitochondrial biogenesis (PGC-1α)

Muscle atrophy

downin mice1

1 study

Lentinan decreases muscle atrophy in mice.
“slowing muscle mass and cross-sectional area loss”
Animalsin aged mice
Lentinan mitigates age-related sarcopenia through the promotion of mitochondrial biogenesis
Food research international (Ottawa, Ont.)16 Jan 2026

Latest

1 in 12 months

Food Research International18 Feb

Lentinan mitigates age-related sarcopenia through the promotion of mitochondrial biogenesis

Experiments in miceSarcopenia

Paper

Lentinan

Outcomes

Latest

Lentinan mitigates age-related sarcopenia through the promotion of mitochondrial biogenesis

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