Lacticaseibacillus casei
Lacticaseibacillus casei has been studied in 2 papers since 2024: none in people yet, 2 in animals. The research so far is in animals. The newest paper, Jul 1, 2025: “Lacticaseibacillus casei HY2782 improves the intestinal barrier and tract environment and ultimately prolongs the lifespan of Caenorhabditis elegans”.
- 1 lab in 1 country
- Funders: Korea Evaluation Institute of Industrial Technology and 2 more
- Model organisms2
What did studies of Lacticaseibacillus casei find?
3Studies of Lacticaseibacillus casei measured 3 outcomes; the most studied are intestinal permeability (1 study), lifespan (1) and inflammation (1).
Intestinal permeability
downin human cells1downin worms1
1 study
Intestinal permeability
downin human cells1downin worms1
Lacticaseibacillus casei decreases intestinal permeability in worms.
“Additionally, L. casei HY2872 attenuated intestinal leakage in C. elegans and prolonged its lifespan via the DAF-16/FOXO and SKN-1/NRF2 pathways and gst-4 gene expression.”
Model organisms
Food & function
Lacticaseibacillus casei decreases intestinal permeability in human cells (265.5 to 115.1%, p < 0.01).
“L. casei HY2782 reduced IL-8 production and intestinal permeability from 1646.8 to 1009.1 pg mL−1 and 265.5 to 115.1%, respectively (p < 0.01).”
Cells
Food & function
Lifespan
upin worms1
1 study
Lifespan
upin worms1
Lacticaseibacillus casei extends lifespan in worms.
“Additionally, L. casei HY2872 attenuated intestinal leakage in C. elegans and prolonged its lifespan via the DAF-16/FOXO and SKN-1/NRF2 pathways and gst-4 gene expression.”
Model organisms
Food & function
Inflammation
downin human cells1
1 study
Inflammation
downin human cells1
Lacticaseibacillus casei decreases inflammation in human cells (from 1646.8 to 1009.1 pg mL−1, p < 0.01).
“L. casei HY2782 reduced IL-8 production and intestinal permeability from 1646.8 to 1009.1 pg mL−1 and 265.5 to 115.1%, respectively (p < 0.01).”
Cells
Food & function