Isometric handgrip training
Intervention1 paper3 findings
- Human trial1
Outcomes
3Aortic pulse wave velocity
no changein humans1Moderate certainty
1 study
Aortic pulse wave velocity
no changein humans1Moderate certainty
Isometric handgrip training has no effect on aortic pulse wave velocity in humans (P > 0.05).
Human trialelevated blood pressure and hypertension8 weeksn = 84
Effects of home-based isometric handgrip or aerobic training on blood pressure variability and vascular health in older adults with elevated blood pressure and hypertension: secondary results from The HoldAge Trial · Blood pressure monitoring · 27 Aug 2026
Flow-mediated dilation
no changein humans1Moderate certainty
1 study
Flow-mediated dilation
no changein humans1Moderate certainty
Isometric handgrip training has no effect on flow-mediated dilation in humans (P > 0.05).
Human trialelevated blood pressure and hypertension8 weeksn = 84
Effects of home-based isometric handgrip or aerobic training on blood pressure variability and vascular health in older adults with elevated blood pressure and hypertension: secondary results from The HoldAge Trial · Blood pressure monitoring · 27 Aug 2026
Nighttime systolic blood pressure variability
downin humans1Moderate certainty
1 study
Nighttime systolic blood pressure variability
downin humans1Moderate certainty
Isometric handgrip training decreases nighttime systolic blood pressure variability in humans (-1.5 ± 3.0 mmHg, P = 0.011).
Human trialelevated blood pressure and hypertension8 weeksn = 84
Effects of home-based isometric handgrip or aerobic training on blood pressure variability and vascular health in older adults with elevated blood pressure and hypertension: secondary results from The HoldAge Trial · Blood pressure monitoring · 27 Aug 2026