Ishige okamurae

Intervention

2 papers study it5 findings

  • 1 lab in 1 country
  • Funders: Pusan National University Hospital and 5 more
  • Human trial1
  • Animals1

Outcomes

4

Lean mass

upin mice2

2 studies
  1. Ishige okamurae increases lean mass in mice.

    “Muscular regeneration parameters, such as lean-mass (p<0.0001), inhibition of proteolysis (measured by changes in myogenin and atrogin-1 protein expressions), cross-sectional myofiber area (p<0.0001)”

    Animalsskeletal muscle50, 100, 200 mg/kg6-weeksmales

    A Combination Study of Pre- and Clinical Trial: Seaweed Consumption Reduces Aging-Associated Muscle Loss!

    Aging and diseaseNov 28, 2023

  2. Ishige okamurae increases lean mass in mice.

    “lean mass increase in aging mice following IO extract and DPHC administration”

    Animalsextractfemales

    Reversibility of sarcopenia by Ishige okamurae and its active derivative diphloroethohydroxycarmalol in female aging mice

    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapieJun 8, 2022

Grip strength

upin mice1

1 study
  1. Ishige okamurae improves grip strength in mice.

    “In 12-month-old male mice, IO administration improved age-related deficiencies in grip strength (p<0.0001) and testosterone (p=0.0001).”

    Animals50, 100, 200 mg/kg6-weeksmales

    A Combination Study of Pre- and Clinical Trial: Seaweed Consumption Reduces Aging-Associated Muscle Loss!

    Aging and diseaseNov 28, 2023

Quadriceps muscle strength

upin humans1

1 study
  1. Ishige okamurae improves quadriceps muscle strength in humans.

    “The IO group exhibited a remarkable increase in lower-limb quadriceps muscle-strength compared to the control (p=0.002).”

    Human triallower-limb quadriceps500 mg/kg12-weeks

    A Combination Study of Pre- and Clinical Trial: Seaweed Consumption Reduces Aging-Associated Muscle Loss!

    Aging and diseaseNov 28, 2023

Physical exercise ability

upin mice1

1 study
  1. Ishige okamurae improves physical exercise ability in mice.

    “the mice model showed a substantial restoration of physical exercise ability”

    Animalsextractfemales

    Reversibility of sarcopenia by Ishige okamurae and its active derivative diphloroethohydroxycarmalol in female aging mice

    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapieJun 8, 2022

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