INDOLE-3-CARBINOL

  • 1 lab in 1 country
  • Funder: Ministero dell'Istruzione e del Merito
  • Cells1

Outcomes

2

Senescent cell count

downin human cells1downin mouse cells1

1 study
  1. INDOLE-3-CARBINOL decreases senescent cell count in human cells.

    “dramatically reducing the number of senescent cells through the induction of apoptosis in both mouse and human primary cells.”

    Cellsthrough induction of apoptosisprimary dermal fibroblast

    The Senolytic Effect of Indole-3-Carbinol (I3C) on Mouse Embryonic (MEF) and Human Fibroblast Cell Lines

    International journal of molecular sciences30 Oct 2024

  2. INDOLE-3-CARBINOL decreases senescent cell count in mouse cells.

    “dramatically reducing the number of senescent cells through the induction of apoptosis in both mouse and human primary cells.”

    Cellsthrough induction of apoptosisembryonic fibroblast

    The Senolytic Effect of Indole-3-Carbinol (I3C) on Mouse Embryonic (MEF) and Human Fibroblast Cell Lines

    International journal of molecular sciences30 Oct 2024

More on Senescent cell count

Cellular senescence

upin human cells1upin mouse cells1

1 study
  1. INDOLE-3-CARBINOL increases cellular senescence in human cells.

    “Here, we surprisingly show that I3C does increase cellular senescence at early passages”

    Cellsat early passagesprimary dermal fibroblast

    The Senolytic Effect of Indole-3-Carbinol (I3C) on Mouse Embryonic (MEF) and Human Fibroblast Cell Lines

    International journal of molecular sciences30 Oct 2024

  2. INDOLE-3-CARBINOL increases cellular senescence in mouse cells.

    “Here, we surprisingly show that I3C does increase cellular senescence at early passages”

    Cellsat early passagesembryonic fibroblast

    The Senolytic Effect of Indole-3-Carbinol (I3C) on Mouse Embryonic (MEF) and Human Fibroblast Cell Lines

    International journal of molecular sciences30 Oct 2024

More on Cellular senescence

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