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Honokiol + NAD+

Intervention

1 paper3 findings

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

  • 1 lab in 1 country
  • Funder: U.S. Department of Defense
  • Animals1

Outcomes

3

SIRT3

upin rats1

1 study

  1. Honokiol + NAD+ increases SIRT3 in rats.

    “primarily by restoring SIRT3 levels in skeletal muscles”

    Animalsin a Sugen/Hypoxia-induced PH rat modelskeletal muscle

    Honokiol and Nicotinamide Adenine Dinucleotide Improve Exercise Endurance in Pulmonary Hypertensive Rats Through Increasing SIRT3 Function in Skeletal Muscle

    International journal of molecular sciencesOct 29, 2024

More on SIRT3

Muscle atrophy

downin rats1

1 study

  1. Honokiol + NAD+ decreases muscle atrophy in rats.

    “reducing proteolysis and atrophy in the gastrocnemius”

    Animalsin a Sugen/Hypoxia-induced PH rat modelgastrocnemius

    Honokiol and Nicotinamide Adenine Dinucleotide Improve Exercise Endurance in Pulmonary Hypertensive Rats Through Increasing SIRT3 Function in Skeletal Muscle

    International journal of molecular sciencesOct 29, 2024

Exercise endurance

upin rats1

1 study

  1. Honokiol + NAD+ improves exercise endurance in rats.

    “Treatment with Honokiol and NAD notably improved exercise endurance”

    Animalsin a Sugen/Hypoxia-induced PH rat model

    Honokiol and Nicotinamide Adenine Dinucleotide Improve Exercise Endurance in Pulmonary Hypertensive Rats Through Increasing SIRT3 Function in Skeletal Muscle

    International journal of molecular sciencesOct 29, 2024

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