HalofuginoneIntervention1 paperPubChemMeSHModel organisms1Mouse lifespanNIA ITP20210.6 ppm from 7 months+8.8% males, +0.2% femalesLatestNov 2025: 0Dec 2025: 0Jan 2026: 1Feb 2026: 0Mar 2026: 0Apr 2026: 0May 2026: 0Jun 2026: 0Jul 2026: 0Aug 2026: 0Sep 2026: 0Oct 2026: 01 in 12 monthsBiomolecules·28 JanNovel tRNA Synthetase Inhibitors Increase Healthspan, Lifespan, and Autophagic Flux in C. elegansExperiments in wormsInterventionsPaperGeroScience·20 SepExtension of lifespan by epicatechin, halofuginone and mitoglitazone in male but not female genetically heterogeneous miceExperiments in animalsInterventionsPaper
Biomolecules·28 JanNovel tRNA Synthetase Inhibitors Increase Healthspan, Lifespan, and Autophagic Flux in C. elegansExperiments in wormsInterventionsPaper
GeroScience·20 SepExtension of lifespan by epicatechin, halofuginone and mitoglitazone in male but not female genetically heterogeneous miceExperiments in animalsInterventionsPaper