Mitoglitazone

Intervention

1 paper1 finding

  • 1 lab
  • Animals1

Mouse lifespan

NIA ITP

Outcomes

1

Lifespan

downin mice1

1 study
  1. Mitoglitazone shortens lifespan in mice.

    “In females, astaxanthin, late-start mitoglitazone, and pioglitazone were associated with significantly reduced lifespan when pooling the data from all three sites.”

    AnimalsUM-HET3 mice; pooled analysis of all three sites; negative effect also observed after excluding The Jackson Laboratoryfemales

    Astaxanthin, meclizine, mitoglitazone, pioglitazone, alpha-ketoglutarate, mifepristone, methotrexate, and atorvastatin-telmisartan do not increase lifespan in UM-HET3 mice

    GeroScience17 Mar 2026

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