Gzmk receptor inhibitors

Intervention

1 paper2 findings

  • 1 lab in 1 country
  • Funders: National Key Research and Development Program of China and 1 more
  • Animals1

Outcomes

2

ER unfolded protein response

downin mice1

1 study
  1. Gzmk receptor inhibitors inhibit ER unfolded protein response in mice.

    “The inhibition of GZMK receptors by small chemical molecules counteracted the UPR and senescence”

    Animalsin functional endocrine cells

    A single-cell transcriptomic landscape characterizes the endocrine system aging in the mouse

    Protein & cell3 Sep 2025

More on ER unfolded protein response

Cellular senescence

downin mice1

1 study
  1. Gzmk receptor inhibitors inhibit cellular senescence in mice.

    “The inhibition of GZMK receptors by small chemical molecules counteracted the UPR and senescence”

    Animalsin functional endocrine cells

    A single-cell transcriptomic landscape characterizes the endocrine system aging in the mouse

    Protein & cell3 Sep 2025

More on Cellular senescence

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