Glycyl-l-histidyl-l-lysine
Across all fields, 3 papers: none in people yet, 1 in animals, 2 reviews
- 1 lab in 1 country
- Funders: National Institute on Aging and 1 more
- Animals1
Outcomes
6Apoptosis
upin reviews1
1 study
Apoptosis
upin reviews1
Glycyl-l-histidyl-l-lysine induces apoptosis.
“reversing cellular senescence and inducing apoptosis in myofibroblasts”
Reviewin myofibroblasts
Aging pathobiology and therapeutics
Cellular senescence
downin reviews1
1 study
Cellular senescence
downin reviews1
Glycyl-l-histidyl-l-lysine decreases cellular senescence.
“GHK (glycyl-L-histidyl-L-lysine], a naturally occurring peptide, has demonstrated the potential in modulating fibrotic pathways by reversing cellular senescence”
Reviewin myofibroblasts
Aging pathobiology and therapeutics
Nitrotyrosine
downin mice1
1 study
Nitrotyrosine
downin mice1
Glycyl-l-histidyl-l-lysine decreases nitrotyrosine in mice.
“GHK prevented an increase in MCP-1 and nitrotyrosine levels in the hippocampus of sleep-deprived mice”
Animalsin sleep-deprived aging micehippocampus15 mg/kg per day5 days
GHK peptide prevents sleep-deprived learning impairment in aging mice
Aging pathobiology and therapeutics
MCP-1
downin mice1
1 study
MCP-1
downin mice1
Glycyl-l-histidyl-l-lysine decreases MCP-1 in mice.
“GHK prevented an increase in MCP-1 and nitrotyrosine levels in the hippocampus of sleep-deprived mice”
Animalsin sleep-deprived aging micehippocampus15 mg/kg per day5 days
GHK peptide prevents sleep-deprived learning impairment in aging mice
Aging pathobiology and therapeutics
Cognitive function
downin mice1
1 study
Cognitive function
downin mice1
Glycyl-l-histidyl-l-lysine protects against cognitive function in mice.
“Sleep-deprived mice treated with GHK did not show the acute learning impairment seen in sleep-deprived mice treated with saline.”
Animalsin sleep-deprived aging micehippocampus15 mg/kg per day5 days
GHK peptide prevents sleep-deprived learning impairment in aging mice
Aging pathobiology and therapeutics
Cognitive impairment
downin mice1
1 study
Cognitive impairment
downin mice1
Glycyl-l-histidyl-l-lysine decreases cognitive impairment in mice.
“preliminary observations suggest GHK can partially reverse cognitive impairment in aging mice”
Reviewin aging mice
The potential of GHK as an anti-aging peptide
Aging pathobiology and therapeutics