Glucose deprivation

1. Glucose deprivation increases reactive oxygen species.

   “Both glucose deprivation and replicative senescence elevate levels of reactive oxygen species (ROS), affecting lysosomal acidification.”

   Reviewin glucose-deprived and replicatively senescent cells

   Impaired Autophagic Flux in Glucose-Deprived Cells: An Outcome of Lysosomal Acidification Failure Exacerbated by Mitophagy Dysfunction

   Molecules and cells·Oct 23, 2023

More on Reactive oxygen species

1. Glucose deprivation impairs autophagy.

   “Autophagy is activated, but its flux is hindered at the autolysis step, primarily due to an impairment of lysosomal acidity.”

   Reviewin glucose-deprived cells

   Impaired Autophagic Flux in Glucose-Deprived Cells: An Outcome of Lysosomal Acidification Failure Exacerbated by Mitophagy Dysfunction

   Molecules and cells·Oct 23, 2023

More on Autophagy