Geniposide
- 1 lab in 1 country
- Funder: Korea Food Research Institute
- Animals1
Outcomes
6FOXO signalling
downin mouse cells1
1 study
FOXO signalling
downin mouse cells1
Geniposide inhibits FOXO signalling in mouse cells.
“inhibited FoxO1 activity by activating AKT”
Cellsin differentiated C2C12 cells
Phytomedicine : international journal of phytotherapy and phytopharmacology12 Dec 2023
Muscle atrophy
downin mouse cells1
1 study
Muscle atrophy
downin mouse cells1
Geniposide decreases muscle atrophy in mouse cells.
“GP ameliorated muscle atrophy induced by dexamethasone treatment”
Cellsin dexamethasone-treated differentiated C2C12 cells
Phytomedicine : international journal of phytotherapy and phytopharmacology12 Dec 2023
Physical function
upin mice1
1 study
Physical function
upin mice1
Geniposide improves physical function in mice.
“ameliorated physical function deterioration”
Animalsaccelerated aging
Phytomedicine : international journal of phytotherapy and phytopharmacology12 Dec 2023
Cognitive function
no changein mice1
1 study
Cognitive function
no changein mice1
Geniposide has no effect on cognitive function in mice.
“In SAMP8 mice, GP did not improve cognitive function deterioration by accelerated aging”
Animalsaccelerated aging
Phytomedicine : international journal of phytotherapy and phytopharmacology12 Dec 2023
Motility
upin worms1
1 study
Motility
upin worms1
Geniposide improves motility in worms.
“significantly restored the observed deterioration in lifespan and motility”
Model organismsin AD model
Phytomedicine : international journal of phytotherapy and phytopharmacology12 Dec 2023
Lifespan
upin worms1
1 study
Lifespan
upin worms1
Geniposide extends lifespan in worms.
“GP treatment in the AD model of C. elegans significantly restored the observed deterioration in lifespan”
Model organismsin AD model
Phytomedicine : international journal of phytotherapy and phytopharmacology12 Dec 2023