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Fibro-adipogenic progenitors

Intervention

1 paper studies it2 findings

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

  • 1 lab in 1 country
  • Funders: Bundesministerium für Bildung und Forschung and 2 more
  • Animals1

Outcomes

2

Inflammation

downin mice1

1 study

  1. Fibro-adipogenic progenitors decrease inflammation in mice.

    “Transplantation of young FAPs with high Periostin secretion, but not Periostin-deficient FAPs, into aged muscle restores inflammation resolution and successful regeneration.”

    Animalsskeletal muscle

    Aging impairs skeletal muscle regeneration by promoting fibro/fatty degeneration and inhibiting inflammation resolution via fibro-adipogenic progenitors

    bioRxiv (Cold Spring Harbor Laboratory)Nov 27, 2023Preprint

More on Inflammation

Skeletal muscle regeneration

upin mice1

1 study

  1. Fibro-adipogenic progenitors improve skeletal muscle regeneration in mice.

    “Transplantation of young FAPs with high Periostin secretion, but not Periostin-deficient FAPs, into aged muscle restores inflammation resolution and successful regeneration.”

    Animalsskeletal muscle

    Aging impairs skeletal muscle regeneration by promoting fibro/fatty degeneration and inhibiting inflammation resolution via fibro-adipogenic progenitors

    bioRxiv (Cold Spring Harbor Laboratory)Nov 27, 2023Preprint

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