Exposure
Intervention2 papers2 findings
- Humans1
- In silico1
Associations
2Horvath clock
upin humans1Very low certainty
1 study
Horvath clock
upin humans1Very low certainty
Exposure is associated with Horvath clock in humans.
“Greater distance to leisure services was associated with older biological age on Horvaths clock and PhenoAge.”
Humansn = 3,307
Multidomain residential external exposome and epigenetic ageing in the UK general population · medRxiv · 16 Sep 2026 · Preprint
Somatic mutations
upin silico1Very low certainty
1 study
Somatic mutations
upin silico1Very low certainty
Exposure is associated with somatic mutations in silico.
In silicoin several tissues
Motif-centered analyses reveal universal and tissue-specific mutagenic mechanisms operating in the human body · NAR cancer · 7 Sep 2026
Funding
National Institute of Environmental Health SciencesUS$22.5mNational Institute on AgingUS$14.2mNational Institute of Neurological Disorders and StrokeUS$2.5m75 grants since 2009
Fine particulate matter exposure and small cerebrovascular inflammation
National Institute of Neurological Disorders and StrokeUniversity of Nebraska Medical CenterUS$696.7k2023–2028
Impact of in utero metformin exposure on offspring growth and metabolic outcomes
National Institute of Child Health and Human DevelopmentEast Carolina UniversityUS$685.2k2026–2031
Glyphosate Exposure and Young Adult Metabolic Health: Epigenetic and Oxidative Stress Mechanisms
National Institute of Environmental Health SciencesUniversity of California, BerkeleyUS$806.5k2026–2031
National Institute on AgingUniversity of UtahUS$12026–2031
Juvenile Exposure to High Fructose Diet in Pathogenesis of Adult Neurovascular Dysfunction
National Institute on AgingKansas State UniversityUS$407.7k2026–2028
National Institute on AgingIcahn School of Medicine at Mount SinaiUS$476.9k2026–2028
PFAS Exposure, PFAS Mitigation, and ADRD Biomarkers and Cognition
National Institute of Environmental Health SciencesUniversity of ArizonaUS$762.6k2026–2031
National Institute on AgingUniversity of WashingtonUS$311k2026–2028
Male pesticide exposure, reproductive health and epigenetics
National Institute of Environmental Health SciencesUniversity of Southern CaliforniaUS$609.1k2026–2028