Review
Endocrine and Molecular Mechanisms of Oocyte Aging: From Gonadotropin Signaling to Metabolic and Microenvironmental Dysfunction
Abstract · CC BY
Ovarian aging and oocyte aging are closely interconnected but distinct components of reproductive aging.
- Altered intercellular communication
- Epigenetic alterations
- Mitochondrial dysfunction
- Telomere attrition
- NAD+ metabolism
- Oxidative stress and ROS signalling
- Telomerase and telomere maintenance
- Aneuploidy
- Spontaneous abortion
- Homo sapiens
The paper
Endocrine and Molecular Mechanisms of Oocyte Aging: From Gonadotropin Signaling to Metabolic and Microenvironmental Dysfunction
Fotara M, Moustakli E, Daskalaki MA et al.
Current Issues in Molecular Biology · 19 Sep 2026