EXO-HO-1

1 paper3 findings

1 lab in 1 country

Cells1

Outcomes

3

NF-κB signalling

downin mouse cells1

1 study

EXO-HO-1 inhibits NF-κB signalling in mouse cells.
“Exo and Exo‐HO‐1 repressed IL‐1β mediating the phosphorylation of p65 and nuclear translocation of p65”
Cellsin IL-1β-stimulated NP cells
Heme oxygenase 1‑overexpressing bone marrow mesenchymal stem cell‑derived exosomes suppress interleukin‑1 beta‑induced apoptosis and aging of nucleus pulposus cells
Molecular medicine reports7 Mar 2025

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Senescence-associated beta-galactosidase

downin mouse cells1

1 study

EXO-HO-1 decreases senescence-associated beta-galactosidase in mouse cells.
“Exo and Exo‐HO‐1 both decreased the number of SA‐β‐gal‐positive NP cells”
Cellsin IL-1β-stimulated NP cells
Heme oxygenase 1‑overexpressing bone marrow mesenchymal stem cell‑derived exosomes suppress interleukin‑1 beta‑induced apoptosis and aging of nucleus pulposus cells
Molecular medicine reports7 Mar 2025

More on Senescence-associated beta-galactosidase

Apoptosis

downin mouse cells1

1 study

EXO-HO-1 decreases apoptosis in mouse cells.
“Exo‐HO‐1 markedly repressed IL‐1β‐prompted apoptosis in NP cells”
Cellsin IL-1β-stimulated NP cells
Heme oxygenase 1‑overexpressing bone marrow mesenchymal stem cell‑derived exosomes suppress interleukin‑1 beta‑induced apoptosis and aging of nucleus pulposus cells
Molecular medicine reports7 Mar 2025

More on Apoptosis

Latest

Molecular Medicine Reports7 Mar

Heme oxygenase 1‑overexpressing bone marrow mesenchymal stem cell‑derived exosomes suppress interleukin‑1 beta‑induced apoptosis and aging of nucleus pulposus cells

Experiments in mouse cellsBones and joints