Ethinylestradiol

  • 2 independent labs in 1 country
  • Funders: Conselho Nacional de Desenvolvimento Científico e Tecnológico and 1 more
  • Humans1
  • Animals2

Outcomes

2

Invasive microcarcinomas

upin M. unguiculatus1

1 study
  1. Ethinylestradiol increases invasive microcarcinomas in M. unguiculatus.

    “Hormonal therapy with E2 or EE2 led to the development of epithelial lesions, characterized by an increase in invasive microcarcinomas”

    Animalsunder previous bisphenol A exposuremammary glandfemales

    Estrogen therapies enhance mammary carcinogenesis in aging gerbil females under endocrine disruption

    Molecular and cellular endocrinology17 Dec 2025

Hot flush frequency

downin rhesus monkeys1

1 study
  1. Ethinylestradiol decreases hot flush frequency in rhesus monkeys (2.02 ± 1.23/day vs 7.67 ± 1.69/day).

    “As expected, EE reduced HF frequency to 2.02 ± 1.23/day”

    Animalspost-ovariectomyfemales

    SAT-015 Brain-Selective Estrogen Therapy to Prevent Menopausal Hot Flushes in a Primate Model

    ENDO 2025 abstract22 Oct 2025

Latest

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