AgingResearch.News

Ethanol

InterventionApproved 2018

2 papers4 findings

PubChem 702ChEBI 16236MeSH D000431

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Labs are independent when their papers share no last author and no institution.

Against: findings that point the other way from most findings on the same outcome.

No results posted: trials that ended more than a year ago with no results on ClinicalTrials.gov and no paper in ARN’s record.

Company ties: findings with an author at a company, or from a paper whose competing-interests statement declares ties to one.

  • 1 lab in 1 country
  • 27 trials, 1 with no results posted
  • Funders: Louisiana Biomedical Research Network and 2 more
  • Animals1

Outcomes

4

COL1A1

downin mice1

1 study

  1. Ethanol decreases COL1A1 in mice.

    Animalsfemoral shaft3, 3, 4, and 4.5 g/kgfour consecutive days

    Aging Exacerbates Binge Ethanol-Mediated Bone Toxicity in Mice

    Alcohol, clinical & experimental research1 Aug 2026

More on COL1A1

TNFSF11

upin mice1

1 study

  1. Ethanol increases TNFSF11 in mice.

    Animalsfemoral shaft3, 3, 4, and 4.5 g/kgfour consecutive days

    Aging Exacerbates Binge Ethanol-Mediated Bone Toxicity in Mice

    Alcohol, clinical & experimental research1 Aug 2026

More on TNFSF11

CTX-1

upin mice1

1 study

  1. Ethanol increases CTX-1 in mice.

    Animalsin aging mice3, 3, 4, and 4.5 g/kgfour consecutive days

    Aging Exacerbates Binge Ethanol-Mediated Bone Toxicity in Mice

    Alcohol, clinical & experimental research1 Aug 2026

More on CTX-1

P1NP

downin mice1

1 study

  1. Ethanol decreases P1NP in mice.

    Animalsbinge ethanol exposure3, 3, 4, and 4.5 g/kgfour consecutive days

    Aging Exacerbates Binge Ethanol-Mediated Bone Toxicity in Mice

    Alcohol, clinical & experimental research1 Aug 2026

More on P1NP

Trials

27

Approved

Repurposing

All 17

In trials

  • Coronary disease

    Phase 4Terminated1 trial

  • Sleep Initiation and Maintenance Disorders

    Phase 4Completed1 trial

  • Thyroid cysts

    Phase 4Status unknown1 trial

  • Alcohol Drinking

    Phase 2/3Active, not recruiting3 trials

  • Alcoholic Intoxication

    Phase 2/3Active, not recruiting2 trials

  • Ketosis

    Phase 2/3Active, not recruiting2 trials

Readouts due

Stopped

  • NCT00152308TerminatedCoronary disease

    Slow enrolement

  • NCT00680459TerminatedSepsis

    inability to enroll adequate number of patients

Trial sponsors

Latest

Nov 2025: 0Dec 2025: 0Jan 2026: 0Feb 2026: 0Mar 2026: 0Apr 2026: 0May 2026: 0Jun 2026: 0Jul 2026: 0Aug 2026: 4Sep 2026: 3Oct 2026: 07 in 12 months

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