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Elocalcitol

Intervention

1 paper3 findings

PubChem

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

  • 1 lab in 1 country
  • Funder: Eesti Teadusagentuur
  • Animals1

Outcomes

3

Senescence markers and SASP cytokines

downin mice1

1 study

  1. Elocalcitol decreases senescence markers and SASP cytokines in mice.

    “while reducing senescence markers and SASP cytokines in WT HFD mice.”

    Animalswild-type mice fed a high-fat diet

    Elocalcitol mitigates high-fat diet-induced microglial senescence via miR-146a modulation

    Immunity & ageing : I & A22 Nov 2024

More on Senescence markers and SASP cytokines

Cognitive function

upin mice1

1 study

  1. Elocalcitol improves cognitive function in mice.

    “lowered body weight and improved cognitive function, while reducing senescence markers and SASP cytokines in WT HFD mice.”

    Animalswild-type mice fed a high-fat diet

    Elocalcitol mitigates high-fat diet-induced microglial senescence via miR-146a modulation

    Immunity & ageing : I & A22 Nov 2024

Body weight

downin mice1

1 study

  1. Elocalcitol decreases body weight in mice.

    “lowered body weight and improved cognitive function, while reducing senescence markers and SASP cytokines in WT HFD mice.”

    Animalswild-type mice fed a high-fat diet

    Elocalcitol mitigates high-fat diet-induced microglial senescence via miR-146a modulation

    Immunity & ageing : I & A22 Nov 2024

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