Ebselen
- 2 independent labs in 1 country
- Animals2
- Cells1
Outcomes
2Auditory function
upin mice1
1 study
Auditory function
upin mice1
Ebselen improves auditory function in mice.
“Furthermore, we discovered that the small molecule drug ebselen could reduce degeneration and damage in SGNs and effectively enhance auditory function by activating autophagy”
Animalsin SGNs
Free radical biology & medicine16 Mar 2026
Testicular aging
downin animals1
1 study
Testicular aging
downin animals1
Ebselen decreases testicular aging.
“PRDX1 dysfunction exacerbates testicular and systematic aging in aged mice, which can be alleviated by a 2-cysteine mimic, ebselen”
Animalsin aged mice with PRDX1 dysfunction
Nature communications19 Nov 2025
Latest
4 in 12 monthsFree Radical Biology & Medicine
GPX3 activates autophagy to protect cochlear spiral ganglion neurons from injury in age-related hearing loss
Experiments in miceAutophagy
Biomedicines
Effects of Different Forms of Selenium in Human Umbilical Cord Mesenchymal Stem Cells
Experiments in human cellsSelenium
Journal of Cellular Biochemistry
Rescue of Aging-Dependent Reduction of Claudin-10b Expression by Glutamate in Mouse Intestinal MCE301 Cells
Experiments in mouse cellsGut and microbiome
Nature Communications
PRDX1 promotes testosterone synthesis and attenuates aging via redox regulation of ATG4B to modulate lipophagy
Experiments in miceMechanisms