Papers on dasatinib + quercetin

388 papers8 new in 30 days

Tuesday, April 21

European Journal of HistochemistryApr 21

Senolytics alleviate cyclophosphamide-induced premature ovarian insufficiency by eliminating senescent cells

Experiments in miceSenolytics

Paper

Tuesday, April 14

AutophagyApr 14

Trophoblast aging driven by IL33 deficiency elevates recurrent pregnancy loss risk through SNAP29 lactylation-mediated autophagy impairment

Study in peoplePregnancy loss

Paper

Bone ResearchApr 14

Dasatinib and quercetin senolytic treatment delays early onset intervertebral disc degeneration in SM/J mice

Experiments in miceSenolytics

Paper

Thursday, April 9

INTERANTIONAL JOURNAL OF SCIENTIFIC RESEARCH IN ENGINEERING AND MANAGEMENTApr 9

Quercetin as a Multi-Target Therapeutic Candidate in Amyotrophic Lateral Sclerosis: From Molecular Mechanisms to Nano-Delivery and Senolytic Strategies

ReviewSenolytics

Paper

Tuesday, April 7

Nature AgingApr 7

Extracellular vesicles derived from senescent hepatocytes drive pan-cancer metastasis in aging

Experiments in miceExtracellular vesicles

Paper

Sunday, April 5

Cell MetabolismApr 5

Amygdala astrocyte senescence drives stress-induced anxiety and hyperglycemia

Experiments in miceHyperglycemia

Paper

Wednesday, April 1

FigshareApr 1

Augmented Cheung Glutamatergic Regimen as a Candidate for Investigation in Amyotrophic Lateral Sclerosis

Preprint: commentaryAmyotrophic lateral sclerosis

Paper

Monday, March 30

FigshareMar 30

Augmenting the Cheung Glutamatergic Regimen with a Senescence-Modulator Arm: Mechanistic Rationale for NMN, Intermittent Senolytics, and N-Acetylcysteine in Treatment-Resistant Depression

Preprint: commentarySenolytics

Paper

Saturday, March 28

Experimental NeurologyMar 28

Senolytic therapy ameliorates high-fat diet-induced hippocampal senescence and cognitive decline in mice

Experiments in miceSenolytics

Paper

Thursday, March 26

Journal of PeriodontologyMar 26

Dasatinib and quercetin prevent alveolar bone loss in aged mice

Experiments in 24 miceDasatinib + quercetin

Paper

Monday, March 23

bioRxivMar 23

Suppression of early pro-inflammatory senescent signature post-radiotherapy mitigates chronic bone damage

Preprint: experiments in miceBones and joints

Paper

Sunday, March 22

EBioMedicineMar 22

PPAR-γ suppresses macrophage senescence and allergic airway inflammation through controlling lipid metabolic pathways

Experiments in miceCellular senescence

Paper

Biology of ReproductionMar 22

Reduced fertility induced by MASLD in female mice is improved by senolytic treatment†

Experiments in miceSenolytics

Paper

Wednesday, March 18

PNASMar 18

Senolytic treatment induces oligodendrocyte dysfunction and demyelination in the corpus callosum

Experiments in miceSenolytics

Paper

Tuesday, March 17

Oxford Journal of Student ScholarshipMar 17

A Review of Telomere Biology and Therapeutic Strategies

ReviewInterventions

Paper

Monday, March 16

Frontiers in PharmacologyMar 16

Dasatinib and quercetin mitigate radiation-induced lung injury by eliminating senescent cells in a rat model

Experiments in ratsDasatinib + quercetin

Paper

Wednesday, March 11

npj AgingMar 11

Emerging strategies in senotherapeutics: from broad-spectrum senolysis to precision reprogramming

ReviewInterventions

Paper

Monday, March 2

CirculationMar 2

P16⁺ Cells Drive Adverse Postischemic Cardiac Remodeling Through CCL8-Mediated Recruitment of Cytotoxic Lymphocytes

Experiments in miceInterventions

Paper

Saturday, February 28

Frontiers in BioscienceFeb 28

Neonatal Hyperoxia Induces Metabolic Reprogramming in Senescent Alveolar Macrophages, Leading to Persistent Lung Injury

Experiments in miceLung

Paper

Friday, February 27

International Journal of Molecular SciencesFeb 27

Dermal Fibroblast Senescence: The Central Hub of Skin Aging-From Intrinsic Dysfunction to Microenvironmental Remodeling

ReviewExtracellular matrix remodeling

Paper

Thursday, February 26

The Journals of Gerontology, Series AFeb 26

Sex-specific proteostasis and urothelial responses to senolytic therapy in the aged mouse bladder

Experiments in miceSenolytics

Paper

Wednesday, February 18

JBMR PlusFeb 18

Inflammatory cytokines secreted from senescent periodontal ligament cells influence the osteocyte network in alveolar bone

Experiments in miceBones and joints

Paper

Tuesday, February 3

Cell Death & DiseaseFeb 3

p16-mediated G0/G1 cell cycle arrest leads to SASP and fibrosis in Fuchs endothelial corneal dystrophy

Experiments in human cellsFibrosis

Paper

Friday, January 30

Science China Life SciencesJan 30

Targeting senescent cells in aged adipose tissue induced by ovarian cancer with the NF-κB inhibitor quercetin and resveratrol impedes the growth and metastasis of ovarian cancer

Experiments in animalsDasatinib + quercetin

Paper

Wednesday, January 28

AntioxidantsJan 28

Targeting Aging and Diseases Associated with Ferroptosis and Senescence Through Modulation of Iron, Oxidative Stress and Lipid Peroxidation

ReviewInterventions

Paper

Friday, January 23

Journal of Translational MedicineJan 23

Senescence-induced endothelial-to-mesenchymal transition accelerates the subretinal fibrosis in neovascualr age-related macular degeneration

Experiments in ratsNeovascular age-related macular degeneration

Paper

Thursday, January 22

EBioMedicineJan 22

Senolytics, dasatanib plus quercetin, reduce kidney inflammation, senescent cell abundance, and injury while restoring geroprotective factors in murine diabetic kidney disease

Experiments in miceSenolytics

Paper

Sunday, January 18

Bioengineering & Translational MedicineJan 18

Honokiol-loaded nanomicelles reprogram senescence and immune evasion in hepatocellular carcinoma via SIRT3-mediated mitochondrial stabilization

Experiments in animalsHepatocellular carcinoma

Paper

Saturday, January 3

GSA 2025 AbstractJan 3

Translating Senolytics From Mice to Humans

ReviewSenolytics

Paper

GSA 2025 AbstractJan 3

Senolytics attenuates influenza- induced muscular decline in aged mice

Experiments in miceSenolytics

Paper