Translational Research
Effects of senotherapeutics on gut microbiome dysbiosis and intestinal inflammation in Crohn's disease: A pilot study
Experiments in human cellsCrohn's disease
Papers on dasatinib + quercetin
391 papers7 new in 30 days
Sunday, February 23
Thursday, February 20
Biochimica et Biophysica Acta Molecular Cell Research
Senolytic elimination of senescent cells improved periodontal ligament stem cell-based bone regeneration partially through inhibiting YAP
Experiments in animalsSenolytics
Thursday, February 13
Journal of Prosthodontic Research
Cellular senescence of RANKL⁺ osteoblasts and Th17 cells in severe periodontitis with occlusal trauma
Experiments in ratsPeriodontitis
Saturday, February 1
Monday, January 20
Friday, January 17
Aging Cell
Characterization of Human Senescent Cell Biomarkers for Clinical Trials
Study in peopleBiomarkers
Friday, January 10
Journal of Dental Research
Dasatinib and Quercetin Limit Gingival Senescence, Inflammation, and Bone Loss
Experiments in miceDasatinib + quercetin
Tuesday, January 7
Cell Death and Differentiation
Apoptotic priming in senescence predicts specific senolysis by quantitative analysis of mitochondrial dependencies
Experiments in cellsBiomarkers
Saturday, January 4
Aging Cell
Senolytic treatment attenuates immune cell infiltration without improving IAV outcomes in aged mice
Experiments in miceSenolytics
Wednesday, January 1
GSA 2024 Abstract
SENOLYTIC EFFECTS ON COGNITION, MOBILITY, AND BIOMARKERS IN OLDER ADULTS WITH MCI AND SLOW GAIT: A PILOT STUDY
Non-randomized trial in 12 peopleSenolytics
Friday, December 27
Journal of Biochemistry
Targeting senescent cells for the treatment of age-associated diseases
ReviewInterventions
Sunday, December 8
Friday, December 6
Scientific Reports
Senolytic cocktail dasatinib and quercetin attenuates chronic high altitude hypoxia associated bone loss in mice
Experiments in miceSenolytics
Tuesday, December 3
Mechanisms of Ageing and Development
Senolytics rejuvenate aging cardiomyopathy in human cardiac organoids
Experiments in human cellsSenolytics
Saturday, November 30
Aging Cell
Restoration of hair follicle inductive properties by depletion of senescent cells
Experiments in animalsInterventions
Tuesday, November 19
Molecular Metabolism
Senescent cell depletion alleviates obesity-related metabolic and cardiac disorders
Experiments in miceMetabolic disease
Saturday, November 16
Scientific Reports
The deleterious effects of CDK4/6 inhibition on renal recovery post-acute kidney injury
Experiments in miceAcute kidney injury
Wednesday, November 13
Stem Cell Research & Therapy
Senolysis potentiates endothelial progenitor cell adhesion to and integration into the brain vasculature
Experiments in miceInterventions
Translational Research
Early vascular aging in chronic kidney disease: focus on microvascular maintenance, senescence signature and potential therapeutics
Cross-sectional study of 82 peopleChronic kidney disease
Thursday, October 24
Aging Cell
Senescence landscape in the liver following sepsis and senolytics as potential therapeutics
Experiments in miceSenolytics
Wednesday, October 23
Neurobiology of Disease
Senolytic therapy preserves blood-brain barrier integrity and promotes microglia homeostasis in a tauopathy model
Experiments in miceSenolytics
Monday, October 21
bioRxiv
Senolytic therapy preserves blood-brain barrier integrity and promotes microglia homeostasis in a tauopathy model
Preprint: experiments in miceSenolytics
Tuesday, October 15
Monday, September 30
The Spine Journal
Senolytics cocktail dasatinib and quercetin alleviate chondrocyte senescence and facet joint osteoarthritis in mice
Experiments in miceSenolytics
Friday, September 27
Tuesday, September 24
Monday, September 23
Life Sciences
Effect of senolytic drugs in young female mice chemically induced to estropause
Experiments in miceSenolytics