SENOLYTIC EFFECTS ON COGNITION, MOBILITY, AND BIOMARKERS IN OLDER ADULTS WITH MCI AND SLOW GAIT: A PILOT STUDY
GSA 2024 Abstract
Abstract
One aim of this single-arm pilot study, called the STAMINA Study, evaluates the preliminary effects of two senolytic drugs, Dasatinib and Quercetin (DQ), on phenotypic and biological outcomes in older adults with slow gait speed and mild cognitive impairment.
- Dasatinib + quercetin
- Senescence-associated secretory phenotype (SASP)
- Mild cognitive impairment
- Gait speed
- Montreal Cognitive Assessment
- Humans
