Cycloneolitsol

1. Cycloneolitsol activates autophagy in worms.

   “CL activates autophagy and enhances the antioxidant stress response ability through the SEK-1/PMK-1/SKN-1 signaling pathway.”

   Model organisms

   Cycloneolitsol prolongs the lifespan of Caenorhabditis elegans by SEK-1/PMK-1/SKN-1 pathway and exerts anti-inflammatory effects by NF-κB pathway

   Biogerontology·16 Mar 2026

More on Autophagy

1. Cycloneolitsol extends lifespan in worms.

   “In C. elegans, CL improved Biological Characteristics and prolonged the lifespan without reproductive toxicity.”

   Model organisms

   Cycloneolitsol prolongs the lifespan of Caenorhabditis elegans by SEK-1/PMK-1/SKN-1 pathway and exerts anti-inflammatory effects by NF-κB pathway

   Biogerontology·16 Mar 2026