Compound ZYZ-384

Intervention

1 paper5 findings

  • 1 lab in 1 country
  • Animals1

Outcomes

2

Aging markers

downin animals1downin human cells1downin mouse cells1

1 study
  1. Compound ZYZ-384 decreases aging markers in animals.

    “ZYZ-384 application significantly inhibited levels of aging markers in both senescent cell and senescent animal models while promoting cell proliferation.”

    AnimalsD-galactose-induced subacute senescence and natural senescence animal models

    Small molecule compound ZYZ-384 targets SMYD3 to alleviate aging

    Scientific reports10 Jul 2025

  2. Compound ZYZ-384 decreases aging markers in mouse cells.

    “ZYZ-384 application significantly inhibited levels of aging markers in both senescent cell and senescent animal models while promoting cell proliferation.”

    Cellsangiotensin II-induced senescenceSVEC4-10

    Small molecule compound ZYZ-384 targets SMYD3 to alleviate aging

    Scientific reports10 Jul 2025

  3. Compound ZYZ-384 decreases aging markers in human cells.

    “ZYZ-384 application significantly inhibited levels of aging markers in both senescent cell and senescent animal models while promoting cell proliferation.”

    Cellsangiotensin II-induced senescenceHMEC-1

    Small molecule compound ZYZ-384 targets SMYD3 to alleviate aging

    Scientific reports10 Jul 2025

More on Aging markers

Cell proliferation

upin human cells1upin mouse cells1

1 study
  1. Compound ZYZ-384 increases cell proliferation in mouse cells.

    “ZYZ-384 application significantly inhibited levels of aging markers in both senescent cell and senescent animal models while promoting cell proliferation.”

    Cellsangiotensin II-induced senescenceSVEC4-10

    Small molecule compound ZYZ-384 targets SMYD3 to alleviate aging

    Scientific reports10 Jul 2025

  2. Compound ZYZ-384 increases cell proliferation in human cells.

    “ZYZ-384 application significantly inhibited levels of aging markers in both senescent cell and senescent animal models while promoting cell proliferation.”

    Cellsangiotensin II-induced senescenceHMEC-1

    Small molecule compound ZYZ-384 targets SMYD3 to alleviate aging

    Scientific reports10 Jul 2025

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