Compound B11

1. Compound B11 protects against muscle damage in mice.

   “compound B11 exhibited potential protective effects against fatigue-induced muscle damage, with favorable safety profiles.”

   Animalsfatigue-inducedmuscle

   Discovery of a Nicotinamide Phosphoribosyltransferase (NAMPT) Activator for Improving Muscle Function and Alleviating Fatigue

   Journal of medicinal chemistry·16 Apr 2026

1. Compound B11 improves muscle strength in mice.

   “compound B11 significantly improved exercise endurance and muscle strength of mice.”

   Animalsmuscle

   Discovery of a Nicotinamide Phosphoribosyltransferase (NAMPT) Activator for Improving Muscle Function and Alleviating Fatigue

   Journal of medicinal chemistry·16 Apr 2026

1. Compound B11 improves exercise endurance in mice.

   “compound B11 significantly improved exercise endurance and muscle strength of mice.”

   Animalsmuscle

   Discovery of a Nicotinamide Phosphoribosyltransferase (NAMPT) Activator for Improving Muscle Function and Alleviating Fatigue

   Journal of medicinal chemistry·16 Apr 2026

1. Compound B11 increases NAD+ in cells.

   “compound B11 demonstrated significant NAMPT activation activity, which effectively boosted NAD+ synthesis across multiple cell lines.”

   Cells

   Discovery of a Nicotinamide Phosphoribosyltransferase (NAMPT) Activator for Improving Muscle Function and Alleviating Fatigue

   Journal of medicinal chemistry·16 Apr 2026

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