Commensal bacteria
3 papers study it4 findings
Across all fields, 3 papers: none in people yet, 3 in animals
- 2 independent labs in 2 countries
- Funders: Japan Agency for Medical Research and Development and others
- Animals2
- Model organisms1
Outcomes
4Reproductive window
upin worms1
1 study
Reproductive window
upin worms1
Commensal bacteria increases reproductive window in worms.
“These effects were accompanied by extending the reproductive window”
Model organisms
Natural commensal microbes induce internal hatching in C. elegans
Microbiology spectrum
Internal hatching
upin worms1
1 study
Internal hatching
upin worms1
Commensal bacteria induces internal hatching in worms (28-57% vs <5%).
“four strains (Ochrobactrum BH3, Lelliottia JUb66, Pantoea BIGb0393, and Enterobacter CEent1) induced high levels of internal hatching (28-57%) in C. elegans during late adulthood”
Model organisms
Natural commensal microbes induce internal hatching in C. elegans
Microbiology spectrum
Senescent microglia
upin mice1
1 study
Senescent microglia
upin mice1
Commensal bacteria increases senescent microglia in mice.
“commensal bacteria promote the accumulation of senescent microglia and disease-associated microglia during ageing”
Animalsduring ageing
Communications biology
Cellular senescence
upin mice1
1 study
Cellular senescence
upin mice1
Commensal bacteria induces cellular senescence in mice.
“persistent presence of commensal bacteria gradually induces cellular senescence in gut germinal centre B cells”
Animalspersistent presence of commensal bacteriagut
Bacterial induction of B cell senescence promotes age-related changes in the gut microbiota
Nature cell biology
Funding
1 grant since 2022National Institute of Diabetes and Digestive and Kidney DiseasesUS$403.8k