Coenzyme Q10 + withania somnifera

Intervention

1 paper5 findings

  • 1 lab in 1 country
  • Animals1

Outcomes

4

Dendritic density

upin mice1

1 study
  1. Coenzyme Q10 + withania somnifera increases dendritic density in mice.

    “Females demonstrated particularly pronounced preservation of white matter structure and increased dendritic density”

    Animals5XFAD micebrainfemales

    Multidimensional Neuroprotective Effects of Combined Ubisol-Q10 and Ashwagandha (Withania somnifera) in Male and Female 5XFAD Mice

    Nutrients5 Oct 2026

Inflammation

downin mice1

1 study
  1. Coenzyme Q10 + withania somnifera decreases inflammation in mice.

    “Across these measures, Tonic treatment preserved brain volumes, reduced amyloid pathology and inflammation, and modulated autophagy-associated pathways.”

    Animals5XFAD micebrainmale and females

    Multidimensional Neuroprotective Effects of Combined Ubisol-Q10 and Ashwagandha (Withania somnifera) in Male and Female 5XFAD Mice

    Nutrients5 Oct 2026

More on Inflammation

Amyloid pathology

downin mice1

1 study
  1. Coenzyme Q10 + withania somnifera decreases amyloid pathology in mice.

    “Across these measures, Tonic treatment preserved brain volumes, reduced amyloid pathology and inflammation, and modulated autophagy-associated pathways.”

    Animals5XFAD micebrainmale and females

    Multidimensional Neuroprotective Effects of Combined Ubisol-Q10 and Ashwagandha (Withania somnifera) in Male and Female 5XFAD Mice

    Nutrients5 Oct 2026

Brain volumes

downin mice1

1 study
  1. Coenzyme Q10 + withania somnifera protects against brain volumes in mice.

    “Across these measures, Tonic treatment preserved brain volumes, reduced amyloid pathology and inflammation, and modulated autophagy-associated pathways.”

    Animals5XFAD miceUbisol-Q10 combined with ethanolic Ashwagandha extractbrainmale and females

    Multidimensional Neuroprotective Effects of Combined Ubisol-Q10 and Ashwagandha (Withania somnifera) in Male and Female 5XFAD Mice

    Nutrients5 Oct 2026

Associations

1

autophagy-associated signaling

mixedin mice1

1 study
  1. Coenzyme Q10 + withania somnifera is associated with autophagy-associated signaling in mice.

    “Across these measures, Tonic treatment preserved brain volumes, reduced amyloid pathology and inflammation, and modulated autophagy-associated pathways.”

    Animals5XFAD micebrainmale and females

    Multidimensional Neuroprotective Effects of Combined Ubisol-Q10 and Ashwagandha (Withania somnifera) in Male and Female 5XFAD Mice

    Nutrients5 Oct 2026

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