Clemastine
- 1 lab in 2 countries
- Funders: Cambridge Trust and others
- Cells1
Outcomes
1NMDAR surface expression
upin cells1
1 study
NMDAR surface expression
upin cells1
Clemastine increases NMDAR surface expression in cells.
“clemastine and metformin extend the window of NMDAR surface expression, promoting an NMDAR-rich OPC state.”
Cellsin ageing OPCs
Scientific reports19 Feb 2024
Latest
1 in 12 monthsCurrent Neurology and Neuroscience Reports
The Potential of Rehabilitation to Amplify Experience-Induced Myelin Plasticity and Remyelination in Multiple Sclerosis: A Narrative Review
ReviewMultiple sclerosis
Annals of Neurology
Clemastine Induces Oligodendrocyte Progenitor Pool Exhaustion and Senescence in the Context of Chronic Demyelination in a Rabbit Model
Experiments in animalsInterventions
Scientific Reports
Clemastine and metformin extend the window of NMDA receptor surface expression in ageing oligodendrocyte precursor cells
Experiments in cellsMetformin