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Cinacalcet

Intervention

1 paper studies it1 finding

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

  • 1 lab in 1 country
  • Funders: Agencia Nacional de Investigación y Desarrollo and 3 more
  • Cells1

Outcomes

1

Mitochondrial transmembrane potential

downin human cells1

1 study

  1. Cinacalcet decreases mitochondrial transmembrane potential in human cells.

    “Crucial proteins for mitochondrial function, PGC-1α and OPA1, were decreased with CMcin treatment, concomitant with fragmentation of the mitochondrial network and decreased mitochondrial transmembrane potential.”

    CellsSW872 pre-adipocyte conditioned mediumhepatocyte120 h

    Secretory Factors from Calcium-Sensing Receptor-Activated SW872 Pre-Adipocytes Induce Cellular Senescence and A Mitochondrial Fragmentation-Mediated Inflammatory Response in HepG2 Cells

    International journal of molecular sciencesMar 9, 2023

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