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Chronic viral exposure

Exposure

1 paper1 finding

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

  • 1 lab in 1 country
  • Humans1

Associations

1

GZMK+/GZMB+ effector memory T-cell ratio

mixedin humans1

1 study

  1. Chronic viral exposure is associated with GZMK+/GZMB+ effector memory T-cell ratio in humans.

    “This ratio reflected immune remodeling driven by chronic viral exposure, including CMV, and disease-associated immune dysregulation, with the dominant driver varying across populations.”

    HumansIncluding CMV exposure; dominant driver varied across populationsCD8+ effector memory T cell

    Immune cell ratio linked to healthy and disease-related aging

    Immunity9 Oct 2026

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Immunity

Immune cell ratio linked to healthy and disease-related aging

An observational analysis of 2,609 apparently healthy people linked the balance of two memory immune-cell groups to healthy and disease-associated aging patterns.An observational analysis of 2,609 apparently healthy people linked the balance of two memory immune-cell groups to healthy and disease-associated aging patterns.

Cohort study of 2,609 peopleImmune response
Paper

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