Chronic psychosocial stress

Chronic psychosocial stress has been studied in 5 papers since 2022: 1 observational study in people, 4 reviews; 2 in the past year. The newest paper, Sep 3, 2026: “ACCELERATED BIOLOGICAL AGING: ENVIRONMENTAL, LIFESTYLE, AND SOCIAL DETERMINANTS OF EPIGENETIC AGE ACCELERATION: A SYSTEMATIC REVIEW”.

Exposure

5 papers study it4 findingsUpdated

See all 5 papers on chronic psychosocial stress

At a glance

The findings reach people, from one lab or study. 1 lab in 1 country.

“GDF15 was also higher in participants exposed to chronic psychosocial stressors, including lower educational attainment, lower family income, and higher job strain”
The energetic stress cytokine GDF15 is elevated in the context of chronic and acute psychosocial stressbioRxiv : the preprint server for biology2024doi:10.1101/2024.04.19.590241
Humans: a single group. Cells, worms or flies and mice: nothing yet.
  • 1 lab in 1 country
  • Funders: Baszucki Brain Research Fund and 8 more
  • Humans1

What did studies of chronic psychosocial stress find?

2

Studies of chronic psychosocial stress measured 2 outcomes: telomere length and biological age.

Telomere length

downin humans1

1 study
  1. Chronic psychosocial stress decreases telomere length in humans.

    “chronic psychosocial stress states that measurably shorten telomeres”

    Review

    The Bio-Social Pathology of Modern Urban Life: Loneliness, Social Isolation and Telomere Shortening

    International Journal of Social Science and Human Research

More on Telomere length

Biological age

upin reviews1

1 study
  1. Chronic psychosocial stress increases biological age (chronic adverse conditions).

    “associated with an increased risk of early onset of age-related disease and, recently, with an older biological age”

    Reviewchronic adverse conditions

    Stress-induced biological aging: A review and guide for research priorities

    Brain, behavior, and immunity

What is chronic psychosocial stress linked with?

2

Studies link chronic psychosocial stress with 2 measures: GDF-15 and mortality.

GDF-15

upin humans1

1 study
  1. Chronic psychosocial stress is associated with GDF-15 in humans.

    “GDF15 was also higher in participants exposed to chronic psychosocial stressors, including lower educational attainment, lower family income, and higher job strain”

    Humansplasma

    The energetic stress cytokine GDF15 is elevated in the context of chronic and acute psychosocial stress

    bioRxiv : the preprint server for biologyPreprint

More on GDF-15

Mortality

upin reviews1

1 study
  1. Chronic psychosocial stress raises the risk of mortality.

    “Chronic psychosocial stress increases disease risk and mortality, but the underlying mechanisms remain largely unclear.”

    Review

    The energetic cost of allostasis and allostatic load

    Psychoneuroendocrinology

Latest

Dec 2025: 0Jan 2026: 0Feb 2026: 0Mar 2026: 0Apr 2026: 0May 2026: 1Jun 2026: 0Jul 2026: 0Aug 2026: 0Sep 2026: 1Oct 2026: 0Nov 2026: 02 papers in 12 months