Chiral gold nanoparticles

1. Chiral gold nanoparticles decrease α-synuclein in mice (83.83 ± 4.76 to 8.66 ± 1.79 ng mL−1).

   “alpha-synuclein (α-syn) in cerebrospinal fluid (CFS) decreased from 83.83 ± 4.76 ng mL−1 to 8.66 ± 1.79 ng mL−1 after two months of treatment.”

   AnimalsParkinson's disease micecerebrospinal fluidtwo months

   Photoinduced elimination of senescent microglia cells in vivo by chiral gold nanoparticles

   Chemical science·16 May 2022

More on α-synuclein

1. Chiral gold nanoparticles decrease parkinson's disease symptoms in mice.

   “the elimination of senescent microglia cells in the brain could further alleviate the symptoms of PD mice”

   AnimalsParkinson's disease micetwo months

   Photoinduced elimination of senescent microglia cells in vivo by chiral gold nanoparticles

   Chemical science·16 May 2022

1. Chiral gold nanoparticles decrease senescent microglia in mice.

   “The in vivo injection of chiral NPs successfully confirmed that the elimination of senescent microglia cells in the brain”

   AnimalsParkinson's disease micebraintwo months

   Photoinduced elimination of senescent microglia cells in vivo by chiral gold nanoparticles

   Chemical science·16 May 2022

1. Chiral gold nanoparticles increase senescent microglia elimination efficiency in mouse cells (about 2-fold higher than d-P− nanoparticles).

   “l-P+ NPs exhibited about a 2-fold higher elimination efficiency than d-P− NPs for senescent microglia cells.”

   Cellscompared with d-P− nanoparticlesl-P+ nanoparticlesmicroglia

   Photoinduced elimination of senescent microglia cells in vivo by chiral gold nanoparticles

   Chemical science·16 May 2022