BP-C3

Intervention

2 papers7 findings

  • 1 lab in 1 country
  • Animals1
  • In silico1

Outcomes

6

Lifespan

upin mice1+8.4% to +12%

1 study
  1. BP-C3 extends lifespan in mice (+12.4%).

    “lifespan of the last 10% of animals - by 12.4%”

    Animalsdrinking water0.005%females

    Polyphenolic drug composition based on benzenepolycarboxylic acids (BP-C3) increases life span and inhibits spontaneous tumorigenesis in female SHR mice

    Aging28 Aug 2016

  2. BP-C3 extends lifespan in mice (+8.4%).

    “BP-C3 increased mean lifespan - by 8.4%”

    Animalsdrinking water0.005%females

    Polyphenolic drug composition based on benzenepolycarboxylic acids (BP-C3) increases life span and inhibits spontaneous tumorigenesis in female SHR mice

    Aging28 Aug 2016

Peroxide-decomposing activity

upin mice1

1 study
  1. BP-C3 increases peroxide-decomposing activity in mice.

    “Its effects in vivo include the ability to ameliorate reduction in the peroxide-decomposing activity of RBC lysates from male BALB/c mice treated with 5-fluorouracil.”

    Animalstreated with 5-fluorouracilred blood cellsmales

    Comparative analysis of experimental data about the effects of various polyphenols on lifespan and aging

    Advances in gerontology = Uspekhi gerontologii1 Jan 2019

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Rate of aging

downin mice1

1 study
  1. BP-C3 decreases rate of aging in mice.

    “The effect of the polyphenolic composition BP-C3 on female SHR mice is unique in being associated with a significant decrease in the rate of aging.”

    Animalsfemales

    Comparative analysis of experimental data about the effects of various polyphenols on lifespan and aging

    Advances in gerontology = Uspekhi gerontologii1 Jan 2019

Estrous function

upin mice1

1 study
  1. BP-C3 improves estrous function in mice.

    “postponed age-related switch-off of estrous function”

    Animalsdrinking water0.005%females

    Polyphenolic drug composition based on benzenepolycarboxylic acids (BP-C3) increases life span and inhibits spontaneous tumorigenesis in female SHR mice

    Aging28 Aug 2016

Tumor

downin mice1

1 study
  1. BP-C3 decreases tumor in mice (1.6 times less).

    “total number of tumors of various localizations was 1.6 times less in BP-C3 treated animals.”

    Animalsdrinking water0.005%females

    Polyphenolic drug composition based on benzenepolycarboxylic acids (BP-C3) increases life span and inhibits spontaneous tumorigenesis in female SHR mice

    Aging28 Aug 2016

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Malignant mammary tumor

downin mice1

1 study
  1. BP-C3 decreases malignant mammary tumor in mice (1.5 times less).

    “The number of malignant mammary tumors was 1.5 times less and total number of tumors of various localizations was 1.6 times less in BP-C3 treated animals.”

    Animalsdrinking water0.005%females

    Polyphenolic drug composition based on benzenepolycarboxylic acids (BP-C3) increases life span and inhibits spontaneous tumorigenesis in female SHR mice

    Aging28 Aug 2016

More on Malignant mammary tumor

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