Box a of HMGB1 plasmid

Intervention

1 paper2 findings

  • 1 lab in 1 country
  • Funders: Chulabhorn Research Institute and 2 more
  • Animals1

Outcomes

2

SHBG

upin cynomolgus monkeys1

1 study
  1. Box a of HMGB1 plasmid improves SHBG in cynomolgus monkeys.

    “Notably, the expression levels of key proteins, such as apolipoprotein E (APOE) and sex hormone-binding globulin (SHBG), showed a reversal effect”

    Animalsperimenopausal monkeysplasmidplasmafemales

    Box A of HMGB1 plasmid reverses the age-related changes in the plasma proteomic profile of perimenopausal monkeys

    Scientific reports5 Apr 2026

More on SHBG

APOE

upin cynomolgus monkeys1

1 study
  1. Box a of HMGB1 plasmid improves APOE in cynomolgus monkeys.

    “Notably, the expression levels of key proteins, such as apolipoprotein E (APOE) and sex hormone-binding globulin (SHBG), showed a reversal effect”

    Animalsperimenopausal monkeysplasmidplasmafemales

    Box A of HMGB1 plasmid reverses the age-related changes in the plasma proteomic profile of perimenopausal monkeys

    Scientific reports5 Apr 2026

More on APOE

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