Blood pressure variability
1 paper5 findings
- 1 lab in 1 country
- Humans1
Outcomes
5Fluid cognition
downin humans1
1 study
Fluid cognition
downin humans1
Blood pressure variability impairs fluid cognition in humans (β = -0.211, 95% CI -0.382 to -0.040).
“asleep BPV was negatively associated with fluid cognition (β = -0.211, 95% CI -0.382 to -0.040).”
Humansbrainn = 76
Neurology30 Apr 2026
White matter hyperintensities
upin humans1
1 study
White matter hyperintensities
upin humans1
Blood pressure variability increases white matter hyperintensities in humans.
“The 24-hour BPV positively associated with WMH volume among APOE ε4 carriers only.”
HumansAPOE ε4 carriersbrain
Neurology30 Apr 2026
Blood-brain barrier water exchange rate
downin humans1
1 study
Blood-brain barrier water exchange rate
downin humans1
Blood pressure variability decreases blood-brain barrier water exchange rate in humans (β = -0.180, 95% CI -0.314 to -0.045).
“BPV negatively associated with BBB kw (β = -0.180, 95% CI-0.314 to -0.045, n = 213).”
Humansdementia-free participantsbrainn = 213
Neurology30 Apr 2026
Executive function
downin humans1
1 study
Executive function
downin humans1
Blood pressure variability impairs executive function in humans (β = -0.174, 95% CI -0.299 to -0.049).
“and executive function (24-hour BPV: β = -0.174, 95% CI-0.299 to -0.049”
Humansdementia-free participantsbrainn = 225
Neurology30 Apr 2026
Global cognition
downin humans1
1 study
Global cognition
downin humans1
Blood pressure variability impairs global cognition in humans (β = -0.152, 95% CI 0.278 to -0.027).
“higher 24-hour and awake BPV were associated with poorer global cognition (24-hour BPV: β = -0.152, 95% CI 0.278 to -0.027”
Humansdementia-free participantsbrainn = 225
Neurology30 Apr 2026