Bb-cl-amidine
Across all fields, 1 paper: none in people yet, 1 in cells
- 1 lab in 1 country
- Funder: Cedars-Sinai Medical Center
- Cells1
Outcomes
4COL1A1
downin human cells1
1 study
COL1A1
downin human cells1
Bb-cl-amidine decreases COL1A1 in human cells.
“however, it decreased collagen 1 A expression.”
Cellsin dilated cardiomyopathy myofibroblasts
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Cellular senescence
downin human cells1
1 study
Cellular senescence
downin human cells1
Bb-cl-amidine decreases cellular senescence in human cells.
“decreased senescence by regulating p-53.”
Cellsin dilated cardiomyopathy myofibroblasts
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Apoptosis
upin human cells1
1 study
Apoptosis
upin human cells1
Bb-cl-amidine induces apoptosis in human cells.
“It also augmented the apoptosis by activating caspase-3 and decreased senescence by regulating p-53.”
Cellsin dilated cardiomyopathy myofibroblasts
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Cell migration
downin human cells1
1 study
Cell migration
downin human cells1
Bb-cl-amidine decreases cell migration in human cells.
“BB-Cl-amidine-mediated PAD inhibition directly affected the cell biology of DCM myofibroblasts, as shown by the reduced migration and invasion of DCM myofibroblasts.”
Cellsin dilated cardiomyopathy myofibroblasts
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie