Bazi bushen capsule

1. Bazi bushen capsule decreases hypoxanthine in mice.

   “imperatorin/isopimpinellin regulated hepatic purine nucleoside phosphorylase (PNP)/hypoxanthine phosphoribosyltransferase 1 (HPRT1) to reduce hypoxanthine”

   Animalsliver

   Modulating hepatic hypoxanthine metabolism relieve metabolic stress-related neurovascular resilience disturbance via the liver-brain axis

   Free radical biology & medicine·Jul 15, 2026

More on Hypoxanthine

1. Bazi bushen capsule decreases cognitive decline in mice.

   “apparent brain aging-related phenotypes, which were alleviated by nicotinamide mononucleotide (NMN) and BZBS.”

   Animalsin mice under HFHS/CD-induced metabolic stress

   Modulating hepatic hypoxanthine metabolism relieve metabolic stress-related neurovascular resilience disturbance via the liver-brain axis

   Free radical biology & medicine·Jul 15, 2026

1. Bazi bushen capsule has no effect on telomere length in humans.

   “it is not significantly associated with increasing telomere length which is important for healthy aging.”

   Human trial12 weeksn = 530

   The efficacy and safety of Bazi Bushen Capsule in treating premature aging: A randomized, double blind, multicenter, placebo-controlled clinical trial

   Phytomedicine : international journal of phytotherapy and phytopharmacology·Jun 4, 2024

More on Telomere length

1. Bazi bushen capsule increases telomerase activity in humans (+150.04 ng/ml).

   “The telomerase content in the BZBS group increased by 150.04 ng/ml compared to the placebo group.”

   Human trial12 weeksn = 530

   The efficacy and safety of Bazi Bushen Capsule in treating premature aging: A randomized, double blind, multicenter, placebo-controlled clinical trial

   Phytomedicine : international journal of phytotherapy and phytopharmacology·Jun 4, 2024

More on Telomerase activity

1. Bazi bushen capsule improves physical function in humans.

   “The FTSST, motor function test grip strength, balance test, walking speed, and muscle mass in the elderly subgroup were all improved in the BZBS group.”

   Human trialin elderly subgroup12 weeks

   The efficacy and safety of Bazi Bushen Capsule in treating premature aging: A randomized, double blind, multicenter, placebo-controlled clinical trial

   Phytomedicine : international journal of phytotherapy and phytopharmacology·Jun 4, 2024

1. Bazi bushen capsule improves quality of life in humans (+98.38 vs +23.79).

   “The SF-36 in the BZBS group increased by 98.38 (23.79 in the placebo group).”

   Human trial12 weeksn = 530

   The efficacy and safety of Bazi Bushen Capsule in treating premature aging: A randomized, double blind, multicenter, placebo-controlled clinical trial

   Phytomedicine : international journal of phytotherapy and phytopharmacology·Jun 4, 2024

1. Bazi bushen capsule decreases frailty in humans (-1.50 vs -0.58).

   “TFI scores in the BZBS group decreased by 13.79 and 1.50 respectively (6.42 and 0.58 in the placebo group, respectively)”

   Human trial12 weeksn = 530

   The efficacy and safety of Bazi Bushen Capsule in treating premature aging: A randomized, double blind, multicenter, placebo-controlled clinical trial

   Phytomedicine : international journal of phytotherapy and phytopharmacology·Jun 4, 2024