Bacillus calmette-guerin

3 papers2 findings

1 lab in 1 country
1 trial, none about aging

Funders: Chan Zuckerberg Initiative and 3 more

Humans1
Animals1

Outcomes

2

Lesion recovery

upin mice1

1 study

Bacillus calmette-guerin improves lesion recovery in mice.
“detected epigenetic reprogramming of brain-resident myeloid cells and functional restoration of myelin debris clearance and lesion recovery.”
Animalscentral nervous system
Innate immune training restores pro-reparative myeloid functions to promote remyelination in the aged central nervous system
ImmunityJul 24, 2024

Myelin debris clearance

upin mice1

1 study

Bacillus calmette-guerin improves myelin debris clearance in mice.
“We used Bacillus Calmette-Guerin (BCG), a live-attenuated vaccine, to train the innate immune system and detected epigenetic reprogramming of brain-resident myeloid cells and functional restoration of myelin debris clearance”
Animalscentral nervous system
Innate immune training restores pro-reparative myeloid functions to promote remyelination in the aged central nervous system
ImmunityJul 24, 2024

Latest

1 in 12 months

Ageing Research ReviewsJun 22

Trained immunity in the treatment for haematological malignancy

ReviewBlood and immune system

ImmunityJul 26

Innate immune training restores pro-reparative myeloid functions to promote remyelination in the aged central nervous system

Experiments in miceBlood and immune system

Cancer Immunology ResearchJun 25

Atypical B Cells Promote Cancer Progression and Poor Response to Bacillus Calmette-Guérin in Non-Muscle Invasive Bladder Cancer

Study in peopleImmune response