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HISTONEDEACETYLASE

Gene

1 paper1 finding

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Includes the processes named after it and trials of drugs aimed at it.

  • 1 lab in 1 country
  • Funders: Chan Zuckerberg Initiative and 3 more
  • Animals1

Effects

1

Remyelination

downin mice1

1 study

  1. HISTONEDEACETYLASE inhibits remyelination in mice.

    “Ablation of two class I histone deacetylases in microglia was sufficient to restore the capacity of aged mice to remyelinate lesioned tissue.”

    Animalscentral nervous system

    Innate immune training restores pro-reparative myeloid functions to promote remyelination in the aged central nervous system

    ImmunityJul 24, 2024

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