Atase inhibitors
1 paper studies it2 findings
- 1 lab in 1 country
- Funders: Eunice Kennedy Shriver National Institute of Child Health and Human Development and 8 more
- Animals1
Outcomes
2Proteopathy
downin mice1
1 study
Proteopathy
downin mice1
Atase inhibitors decrease proteopathy in mice.
“successful ATase inhibitors can rescue the proteopathy of a mouse model of Alzheimer's disease”
Animalsin a mouse model of Alzheimer's disease
ATase inhibition rescues age-associated proteotoxicity of the secretory pathway
Communications biologyFeb 25, 2022
Progeria-like phenotype
downin mice1
1 study
Progeria-like phenotype
downin mice1
Atase inhibitors decrease progeria-like phenotype in mice.
“ATase inhibitors can rescue ongoing disease manifestations associated with the segmental progeria-like phenotype of AT-1 sTg mice”
Animalsin AT-1 sTg mice
ATase inhibition rescues age-associated proteotoxicity of the secretory pathway
Communications biologyFeb 25, 2022
Latest
Communications Biology
ATase inhibition rescues age-associated proteotoxicity of the secretory pathway
Experiments in miceInterventions