Ampicillin + vancomycin + neomycin
Ampicillin + vancomycin + neomycin has been studied in 1 paper since 2025: none in people yet, 1 in animals. The research so far is in animals. The newest paper, Oct 1, 2025: “Antibiotic-Induced Gut Dysbiosis Modulates Alzheimer's Disease-Associated Gene Expression and Protein Aggregation in 3xTg-AD Mice via the Gut-Brain Axis”.
1 paper studies it2 more mention it5 findingsUpdated
See all 3 papers on ampicillin + vancomycin + neomycin
At a glance
The findings reach mice, none yet in people. 1 lab in 1 country.
None of its findings points the other way.
- 1 lab in 1 country
- Funders: Noguchi Memorial Institute for Medical Research and 1 more
- Animals1
What did studies of ampicillin + vancomycin + neomycin find?
5Studies of ampicillin + vancomycin + neomycin measured 5 outcomes; the most studied are TNF-alpha (1 study), tau protein (1) and amyloid-β1–42 (1).
TNF-alpha
upin mice1
1 study
TNF-alpha
upin mice1
Ampicillin + vancomycin + neomycin increases TNF-alpha in mice (antibiotic-induced gut dysbiosis).
“TNF-α was significantly elevated in both regions, indicating neuroinflammation.”
Animalsantibiotic-induced gut dysbiosishippocampus and cerebral cortex14 daysfemales
Brain and behavior
Tau protein
upin mice1
1 study
Tau protein
upin mice1
Ampicillin + vancomycin + neomycin increases tau protein in mice (antibiotic-induced gut dysbiosis).
“Dysbiosis also led to increased brain levels of amyloid-β1−42 and tau.”
Animalsantibiotic-induced gut dysbiosisbrain14 daysfemales
Brain and behavior
Amyloid-β1–42
upin mice1
1 study
Amyloid-β1–42
upin mice1
Ampicillin + vancomycin + neomycin increases amyloid-β1–42 in mice (antibiotic-induced gut dysbiosis).
“Dysbiosis also led to increased brain levels of amyloid-β1−42 and tau.”
Animalsantibiotic-induced gut dysbiosisbrain14 daysfemales
Brain and behavior
Anxiety-like behavior
upin mice1
1 study
Anxiety-like behavior
upin mice1
Ampicillin + vancomycin + neomycin increases anxiety-like behavior in mice (antibiotic-induced gut dysbiosis).
“Dysbiotic mice displayed impaired spatial working memory, heightened anxiety-like behavior, and reduced locomotor activity.”
Animalsantibiotic-induced gut dysbiosis14 daysfemales
Brain and behavior
Spatial working memory
downin mice1
1 study
Spatial working memory
downin mice1
Ampicillin + vancomycin + neomycin impairs spatial working memory in mice (antibiotic-induced gut dysbiosis).
“Dysbiotic mice displayed impaired spatial working memory, heightened anxiety-like behavior, and reduced locomotor activity.”
Animalsantibiotic-induced gut dysbiosis14 daysfemales
Brain and behavior