Ammonia

1 paper3 findings

PubChem ChEBI MeSH

1 lab in 1 country

Outcomes

1

Cellular senescence

upin rat cells1

1 study

Ammonia induces cellular senescence in rat cells.
“In vitro studies of ammonia-treated rat brain endothelial cell line 4 showed senescent features”
Cellsbrain endothelial cells
Unraveling Ammonia-Induced Brain Endothelial Senescence: Role of miRNA-183-5p
Antioxidants & redox signaling23 May 2025

More on Cellular senescence

Associations

2

Proteostasis defects

upin reviews1

1 study

Ammonia is associated with proteostasis defects.
“In this context, ammonia has been implicated in mitochondrial injury, senescence-associated signaling, proteostasis defects, and inflammatory and fibrogenic remodeling.”
Reviewliver
Ammonia Metabolism in the Aging Liver: Emerging Mechanistic Insights
Aging cell21 Jul 2026

Mitochondrial injury

upin reviews1

1 study

Ammonia is associated with mitochondrial injury.
“In this context, ammonia has been implicated in mitochondrial injury, senescence-associated signaling, proteostasis defects, and inflammatory and fibrogenic remodeling.”
Reviewliver
Ammonia Metabolism in the Aging Liver: Emerging Mechanistic Insights
Aging cell21 Jul 2026

Latest

14 in 12 months

Metabolites24 Sep

Exercise as a Multisystem Adjunct for Alcohol-Associated Liver Disease: Inflammatory Mechanisms, Muscle-Liver Crosstalk, and Translational Gaps

Frontiers in Microbiology12 Aug

Different ages of gut microbiota diversity and metabolic pattern in rhesus macaques

Experiments in monkeysShort-chain fatty acid metabolism

Cureus11 Aug

Effect of an Integrated Exercise Training Program on Muscle Mass and Functional Capacity in Sarcopenic Patients With Decompensated Liver Cirrhosis

Randomised trial in 40 peopleExercise

Problemy Endokrinologii3 Aug

Metformin's disruption of gluconeogenesis in type 2 diabetes impairments of the cori and alanine cycles as hidden drivers of metabolic waste accumulation, NF-κBHIF-1α-mediated low-grade inflammation, and multisystem dysfunction

ReviewMetformin

Aging Cell21 Jul

Ammonia Metabolism in the Aging Liver: Emerging Mechanistic Insights

ReviewMechanisms

ADA Scientific Sessions 2026 Abstract6 Jun

Effect of Luseogliflozin on Myocardial Flow Reserve in Patients with Type 2 Diabetes Mellitus (LUCENT-J Study)

Randomised trial in 40 peopleDiabetes mellitus

Molecular Nutrition & Food Research1 Jun

Early-Life Obesity Leaves a Metabolic Memory That Accelerates Aging-Related Decline Through the Gut Microbiota-GABA Axis

Experiments in ratsGut and microbiome

Canadian Journal of Zoology23 Apr

Hibernation-Inspired Innovations in Biomedicine: Addressing Aging, Chronic Diseases, and Critical Care

ReviewMechanisms

Cell Communication and Signaling2 Apr

The cGAS-STING pathway in senescence and aging-related diseases: mechanisms and therapeutic opportunities

ReviewcGAS–STING signalling

Biology Direct11 Mar

The impact of mesenchymal stromal cells on the proliferation and functional maturation of liver organoids

Experiments in animalsInterventions