AAV9-ETV5

Intervention

1 paper2 findings

  • 1 lab in 1 country
  • Funder: Natural Science Foundation of Hubei Province
  • Animals1

Outcomes

2

Pyroptosis

downin mice1

1 study
  1. AAV9-ETV5 inhibits pyroptosis in mice.

    “ETV5 overexpression attenuated cognitive impairment, enhanced antioxidant capacity, and hampered caspase-3/GSDME-mediated pyroptosis”

    Animalsin laparotomy under isoflurane anesthesia modelhippocampus

    ETV5 transcriptionally inhibits KIF23 to repress pyroptosis in aged mice with perioperative neurocognitive disorders

    Biochemical pharmacology20 Sep 2025

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Perioperative neurocognitive disorder

downin mice1

1 study
  1. AAV9-ETV5 protects against perioperative neurocognitive disorder in mice.

    “ETV5 overexpression attenuated cognitive impairment, enhanced antioxidant capacity, and hampered caspase-3/GSDME-mediated pyroptosis”

    Animalsin laparotomy under isoflurane anesthesia modelhippocampus

    ETV5 transcriptionally inhibits KIF23 to repress pyroptosis in aged mice with perioperative neurocognitive disorders

    Biochemical pharmacology20 Sep 2025

More on Perioperative neurocognitive disorder

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