ETV5

1. ETV5 inhibits KIF23 in mouse cells.

   “ETV5 directly bound to the sequence spanning from 1 to 700 bp upstream of the KIF23 gene transcription initiation site and repressed its transcription”

   Cellsspanning from 1 to 700 bp upstream of the transcription initiation site

   ETV5 transcriptionally inhibits KIF23 to repress pyroptosis in aged mice with perioperative neurocognitive disorders

   Biochemical pharmacology·20 Sep 2025

More on KIF23

1. ETV5 inhibits pyroptosis in mouse cells.

   “diminished the release of IL-1β, IL-18, and LDH”

   Cellsunder isoflurane and LPS conditions

   ETV5 transcriptionally inhibits KIF23 to repress pyroptosis in aged mice with perioperative neurocognitive disorders

   Biochemical pharmacology·20 Sep 2025

More on Pyroptosis