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AAV-SH-SDRNA-D43

Intervention

1 paper1 finding

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

  • 1 lab in 1 country
  • Funder: National Natural Science Foundation of China
  • Humans1

Outcomes

1

Osteoarthritis

downin rats1

1 study

  1. AAV-SH-SDRNA-D43 decreases osteoarthritis in rats.

    “Additionally, injection of AAV-sh-sdRNA-D43 alleviated the progression of OA in a monosodium iodoacetate-induced rat model.”

    Animalsmonosodium iodoacetate-induced osteoarthritisknee joint

    sdRNA-D43 derived from small nucleolar RNA snoRD43 improves chondrocyte senescence and osteoarthritis progression by negatively regulating PINK1/Parkin-mediated mitophagy pathway via dual-targeting NRF1 and WIPI2

    Cell communication and signaling : CCS11 Feb 2025

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