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SDRNA-D43

Gene

1 paper2 findings

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Includes the processes named after it and trials of drugs aimed at it.

  • 1 lab in 1 country
  • Funder: National Natural Science Foundation of China
  • Humans1

Effects

2

Mitophagy

downin human cells1

1 study

  1. SDRNA-D43 inhibits mitophagy in human cells.

    “sdRNA-D43 inhibited mitophagy and promoted chondrocytes senescence during OA progression.”

    Cellschondrocyte

    sdRNA-D43 derived from small nucleolar RNA snoRD43 improves chondrocyte senescence and osteoarthritis progression by negatively regulating PINK1/Parkin-mediated mitophagy pathway via dual-targeting NRF1 and WIPI2

    Cell communication and signaling : CCS11 Feb 2025

More on Mitophagy

Cellular senescence

upin human cells1

1 study

  1. SDRNA-D43 induces cellular senescence in human cells.

    “sdRNA-D43 inhibited mitophagy and promoted chondrocytes senescence during OA progression.”

    Cellschondrocyte

    sdRNA-D43 derived from small nucleolar RNA snoRD43 improves chondrocyte senescence and osteoarthritis progression by negatively regulating PINK1/Parkin-mediated mitophagy pathway via dual-targeting NRF1 and WIPI2

    Cell communication and signaling : CCS11 Feb 2025

More on Cellular senescence

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