Aav-osk

Intervention

1 paper3 findings

  • 1 lab in 1 country
  • Animals1

Outcomes

3

Chondrocyte vitality

upin mouse cells1

1 study
  1. Aav-osk improves chondrocyte vitality in mouse cells.

    “AAV-OSK significantly preserved chondrocyte vitality in an inflammatory environment”

    Cellsinflammatory environment

    Local delivery of OSK factors enables partial cellular reprogramming to mitigate osteoarthritis and cartilage fibrosis

    Experimental & molecular medicine5 Mar 2026

Cellular senescence

downin mice1

1 study
  1. Aav-osk decreases cellular senescence in mice.

    “Furthermore, chondrocyte senescence and DNA methyltransferase expression were markedly diminished in the AAV-OSK group.”

    Animalscartilage

    Local delivery of OSK factors enables partial cellular reprogramming to mitigate osteoarthritis and cartilage fibrosis

    Experimental & molecular medicine5 Mar 2026

More on Cellular senescence

Cartilage integrity

upin mice1

1 study
  1. Aav-osk improves cartilage integrity in mice.

    “In OA murine models, AAV-OSK administration led to a notable improvement in cartilage integrity”

    Animalscartilage

    Local delivery of OSK factors enables partial cellular reprogramming to mitigate osteoarthritis and cartilage fibrosis

    Experimental & molecular medicine5 Mar 2026

Latest

Nov 2025: 0Dec 2025: 0Jan 2026: 0Feb 2026: 0Mar 2026: 1Apr 2026: 0May 2026: 0Jun 2026: 0Jul 2026: 0Aug 2026: 0Sep 2026: 0Oct 2026: 01 in 12 months