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3-DZNeP

Intervention

1 paper1 finding

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

  • 1 lab in 1 country
  • Funders: 59th Medical Wing and 7 more
  • Animals1

Outcomes

1

Cellular senescence

upin mice1

1 study

  1. 3-DZNeP induces cellular senescence in mice.

    “Inhibition of EZH2 with its specific inhibitor 3-DZNeP promotes tubular cell senescence and kidney aging”

    Animalsin mouse kidneys

    Downregulation of EZH2 Promotes Renal Epithelial Cellular Senescence and Kidney Aging

    FASEB journal : official publication of the Federation of American Societies for Experimental Biology6 May 2025

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